Depression and Anxiety Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with major depressive disorder (a serious form of depression, without psychosis) — either a first episode or a recurring condition — according to standard psychiatric guidelines (DSM-5)
• People whose depression is rated as moderately severe or above on a standard depression scale called the MADRS (a score of 20 or higher), and who also score above 2 on the part of that scale measuring loss of pleasure or interest
• People who have been on a stable antidepressant medication for at least 4 weeks before joining the trial
• People who are able to speak and read French
• People who have signed a consent form before the trial begins

Who may not be able to join:

• People who have a condition that affects their sense of smell — such as being born without a sense of smell, a current upper respiratory infection, nasal or sinus disease, a brain injury, or previous nasal surgery — or who have a neurological disease
• People who have other psychiatric disorders in addition to depression, or who use substances other than tobacco
• People who have a medical implant or metal object in their head, as these are safety concerns for the brain stimulation treatment (TMS) used in this trial
• People who are pregnant or breastfeeding (this is checked using a urine pregnancy test)
• People who are under a legal protection or guardianship order (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.