Gastro-oesophageal Reflux Disease Trial, Recruiting NCT05696184 Sponsor: Medical College of Wisconsin Condition: Gastro-oesophageal Reflux Disease
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Gastro-oesophageal Reflux Disease Trial, Recruiting

NCT05696184
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 85 years old
  • People diagnosed with gastroesophageal reflux disease (GERD — a condition where stomach acid flows back into the food pipe) who experience regurgitation (stomach contents coming back up) and symptoms in the throat or airways, such as burning throat, chronic cough, hoarseness, or asthma
  • People diagnosed with GERD who do not have throat or airway symptoms, recruited through gastroenterology or ear, nose, and throat clinics
  • People diagnosed with asthma (with or without throat or airway reflux symptoms), including those with mild, moderate, or severe asthma — as long as they are not having an active asthma flare-up at the time of the study
  • People who have been on long-term acid-suppressing medication but still experience ongoing regurgitation and throat or airway symptoms, and who score above 13 on a standard reflux symptom questionnaire
  • People with Barrett's esophagus (a condition affecting the lining of the food pipe) confirmed by a previous tissue biopsy

Who may not be able to join:

  • People younger than 18 or older than 85
  • People with a current problem with alcohol or drug misuse
  • People with a history of ear, nose, throat, or lung conditions that are thought to be caused by acid reflux
  • People with a history of cancer of the head or neck, or who have had chemotherapy or radiation therapy to the head or neck area
  • People who are not able to give their own consent to participate
  • Women who are pregnant
  • People with a known allergy to Lidocaine, a local anaesthetic used as a nasal spray during the study procedure
  • People with an allergy to green food dye
  • People with asthma who are currently experiencing an active flare-up, including symptoms such as breathlessness, wheezing, or chest tightness

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Reza Shaker, MD, Medical College of Wisconsin

Phone: 4149556840

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Medical College of Wisconsin
Registry
ClinicalTrials.gov
Start date
1 November 2013
Est. completion
12 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Pressure Data Analysis; Videoendoscopic data analysis

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov