Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 55 years old
- People whose primary diagnosis is Major Depressive Disorder (MDD) and who are currently experiencing depression
- People who are able to provide written consent before taking part
- People who are either not taking any antidepressant medication, or who have been on a stable antidepressant for at least 4 weeks (existing effective medications would not need to be stopped for this study)
Who may not be able to join:
- People with significant or unstable heart, lung, hormonal, neurological, or digestive system conditions, or other unstable medical conditions
- People with a current severe alcohol or substance use disorder (excluding nicotine or caffeine); the trial team would assess mild or moderate alcohol or substance use on a case-by-case basis to decide if it may affect the study (confirm with trial site)
- People with a history of traumatic brain injury
- People who are unable to have an MRI scan due to claustrophobia or other MRI-related reasons (such as having metal fragments inside the body)
- People who are currently pregnant or breastfeeding
- People who are unable to complete questionnaires written in English
- People who are currently taking (within 3 weeks of testing) antipsychotics, anticonvulsants, stimulants, benzodiazepines, beta-blockers, or other medications likely to affect blood flow in the brain — not including antidepressants, which would not need to be stopped
- People diagnosed with a psychotic or organic mental disorder, or with Bipolar I or II disorder
- People with eye problems or uncorrectable vision difficulties
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kymberly Young, PhD, University of Pittsburgh
Phone: 412-648-6179
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Beck Depression Inventory (BDI-II)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.