Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have a confirmed diagnosis of atrial fibrillation (an irregular heartbeat condition)
- You have had an ischemic stroke (a stroke caused by a blocked blood vessel, not bleeding) — including cases where stroke symptoms went away within 24 hours but a brain scan showed evidence of stroke — and your stroke happened either within the last 6 weeks, or between 6 and 52 weeks ago, depending on whether you were already on blood thinners at the time (confirm with trial site)
- You are planned to take a blood-thinning medication (either warfarin-type or a newer direct oral blood thinner) for the whole duration of the trial
- Your doctor believes you can safely take one antiplatelet medication (such as aspirin) alongside your blood thinner for 6 months
- An ultrasound or imaging scan of your neck arteries shows your arteries meet specific size and health requirements, including no significant narrowing, no tears, and no existing stents in the relevant area (confirm with trial site)
- You are willing and able to give your informed consent to take part
Who may not be able to join:
- You cannot safely take blood-thinning medications — for example, due to a history of bleeding in the brain, a blood clotting disorder, or repeated serious bleeding episodes
- You cannot safely take an antiplatelet medication (such as aspirin) for 6 months
- You have a significant narrowing (50% or more) or dangerous plaque buildup in certain neck or brain arteries that has not been treated with a procedure such as a stent
- Imaging has shown an active blood clot floating freely in your neck or brain arteries that could cause another stroke
- You have a previously identified aneurysm (a bulge in a blood vessel) of 6mm or larger in certain arteries near the brain
- You have had surgery or radiation treatment on the area of the neck where the device would be placed
- You already have a device implanted to close off part of your heart (left atrial appendage) that was put in after your most recent stroke
- You are planning to have a procedure to close off part of your heart (left atrial appendage occlusion)
- You are pregnant, or are a woman who could become pregnant and is not willing to use effective contraception for the duration of the trial
- You currently have an active widespread infection in your body
- You have a known allergy to nickel, titanium, or related metals
- You are currently participating in another clinical trial involving an experimental drug or device
- You have any other health condition that your doctor believes could put you at risk or prevent you from completing the trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ashkan Shoamanesh, MD, FRCPC, Population Health Research Institute, McMaster University
Phone: +972587112116
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Large vessel occlusion strokes (efficacy); Serious device or procedure related complications (safety); ISTH (International Society on Thrombosis and Haemostasis) major bleeding occurring during OAC + clopidogrel intake.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.