Depression and Anxiety Trial, Recruiting NCT05732311 Sponsor: Berthold Langguth, MD, Ph.D. Condition: Depression and Anxiety
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Depression and Anxiety Trial, Recruiting

NCT05732311
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults (men or women) between 18 and 70 years of age who have been diagnosed with a depressive episode, recurring depression, or bipolar disorder
  • People whose depression was rated as moderate or severe before starting the initial treatment in this study (based on a standard depression rating scale score above 16)
  • People who responded well to the initial brain stimulation treatment used in this study — meaning their depression score either dropped by at least half, or fell below 11 points by the end of treatment
  • People who do not have psychotic symptoms (such as hallucinations or delusions) at the time of the study
  • People who do not have any other significant psychiatric conditions, as determined by the study doctor
  • People who live in Germany and speak German well enough to understand the study information
  • People who are able to give their own informed consent to participate

Who may not be able to join:

  • People who have a pacemaker, insulin pump, or any other electrical implants or metal objects inside their body (as these are safety concerns for brain stimulation treatment)
  • People with serious neurological conditions, such as stroke, epilepsy, brain malformations, neurodegenerative diseases, or a history of severe head injury
  • People who are currently misusing or are dependent on alcohol, amphetamines, cocaine, benzodiazepines, anticonvulsants, or opiates
  • People who are currently experiencing acute suicidal thoughts or intent
  • People who are pregnant
  • People who are currently taking part in another clinical study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Berthold Langguth, Prof., University Hospital of Regensburg, Department of Psychiatry and Psychotherapy at the Bezirksklinikum

Phone: +49-941-941-2054

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Berthold Langguth, MD, Ph.D.
Registry
ClinicalTrials.gov
Start date
25 April 2023
Est. completion
31 January 2026

Where this trial is recruiting

🇩🇪 Germany

Primary endpoints

relapse (number of patients who have a relapse for depression)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov