Phase 2 Peripheral Neuropathy Trial, Recruiting NCT05735717 Sponsor: Masonic Cancer Center, University of Minnesota Condition: Peripheral Neuropathy
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Phase 2 Peripheral Neuropathy Trial, Recruiting

NCT05735717
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a blood cancer (such as acute leukemia, acute myeloid leukemia, acute lymphoblastic leukemia/lymphoma, or certain types of myelodysplasia), confirmed by a tissue or bone marrow sample
  • People aged 60 years or younger at the time of signing consent
  • People whose general physical ability and daily functioning meets a minimum health threshold, as measured by standard medical scoring tools (the Karnofsky scale or Lansky play score, depending on age)
  • People whose heart, liver, kidneys, and other organs are working well enough to meet the trial's requirements

Who may not be able to join:

  • People who are pregnant or breastfeeding
  • People who have an active infection that is not under control within one week of starting the preparatory treatment for the trial
  • People who are HIV-positive, or who have an active Hepatitis B or C infection with a detectable level of virus in the blood
  • People who have previously had a stem cell or bone marrow transplant (either from their own cells or from a donor)
  • People whose chronic myeloid leukemia (CML) has progressed to what is known as "blast crisis" stage
  • People who have blood cancer that has spread to the central nervous system (brain or spinal cord) and is currently active

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Margaret MacMillan, Masonic Cancer Center, University of Minnesota

Phone: 612-626-2961

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Masonic Cancer Center, University of Minnesota
Registry
ClinicalTrials.gov
Start date
11 May 2023
Est. completion
30 November 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Determine the rate of GVHD after alpha beta TCR depletion

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov