Parkinson's Disease Trial, Recruiting NCT05740683 Sponsor: Danish Dementia Research Centre Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT05740683
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For patients with idiopathic olfactory dysfunction (unexplained loss of smell):

  • People between 55 and 75 years of age
  • People whose loss of smell has been progressing slowly and steadily, without episodes of getting better or worse
  • People who are able to give informed consent and can cooperate with the study, as assessed by the lead researcher

For healthy control participants:

  • People between 55 and 75 years of age
  • People who are able to give informed consent
  • People who are able to cooperate with the study, as assessed by the lead researcher

Who may not be able to join:

For patients with idiopathic olfactory dysfunction (unexplained loss of smell):

  • People who have been diagnosed with a brain or nerve-related disease, or a major mental health condition
  • People whose loss of smell is caused by nose or sinus problems (such as chronic nasal inflammation or allergies), a head injury, an infection, a condition present from birth, surgery, or medications or toxic substances
  • People whose loss of smell improved when treated with steroid medications (if these were tried)
  • People with severe abnormalities or infections inside the nasal cavity
  • People showing clear signs of dementia or Parkinson's disease
  • People currently misusing alcohol or drugs
  • People with a terminal illness

For healthy control participants:

  • People who show signs of smell problems on a clinical test
  • People showing clear signs of dementia or Parkinson's disease
  • People with severe abnormalities or infections inside the nasal cavity
  • People currently misusing alcohol or drugs
  • People who have been diagnosed with a brain or nerve-related disease, or a major mental health condition

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kristian S Frederiksen, Danish Dementia Research Centre, Rigshospitalet, Capital Region

Phone: +4535458759

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Danish Dementia Research Centre
Registry
ClinicalTrials.gov
Start date
1 February 2023
Est. completion
1 December 2032

Where this trial is recruiting

🇩🇰 Denmark

Primary endpoints

Real-time quaking-induced conversion (RT-QuIC) positive for alpha-synuclein (aSyn); Diagnosis of Parkinson's disease (PD) or dementia

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov