Phase 2 Type 1 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have had type 1 diabetes for at least 5 years
• People who are at risk of low blood sugar levels during the night — either shown by a continuous glucose monitor (CGM) recording blood sugar dropping very low (below 54 mg/dL) for at least 1% of the time over the past 4 weeks, or based on recent history suggesting nighttime low blood sugar, confirmed by a study-provided CGM worn during an extra screening period
• People whose HbA1c blood sugar level (a measure of average blood sugar over several months) is 10.0% or below at the time of screening
• People whose Body Mass Index (BMI) is between 18.5 and below 33 kg/m²

Who may not be able to join:

• People who have been hospitalised for a serious diabetes complication called diabetic ketoacidosis (DKA) more than once in the past 6 months
• People who have had one or more episodes of very severe low blood sugar (needing help from another person to recover) in the past 4 weeks, or more than 2 such episodes in the past 3 months
• People who have been diagnosed with type 2 diabetes, or certain other medical conditions affecting hormones or metabolism (including pheochromocytoma, insulinoma, glucagonoma, acromegaly, Cushing's disease, glycogen storage disease, or adrenal insufficiency)
• People with a significant kidney disease
• People with abnormal liver function

Important: Always verify eligibility with the trial site directly before applying.