Atrial Fibrillation Trial, Recruiting NCT05776797 Sponsor: University Hospital Ostrava Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT05776797
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have a heart device called a cardiac resynchronisation therapy (CRT) pacemaker or defibrillator, and have had it for more than 6 months
  • You have been diagnosed with an irregular heart rhythm called atrial fibrillation (AF), which is either permanent or keeps coming back, and has caused at least one emergency visit or hospital stay in the past year
  • Your heart failure medications and heart rate medications have already been adjusted to the best possible levels
  • If you have permanent AF, your heart device and heartbeat are working within a specific range (between 85% and 99% effective) for at least one month while on your optimised medications (confirm with trial site)
  • You are between 18 and 85 years old
  • You are willing and able to give your signed agreement to take part

Who may not be able to join:

  • You have had a heart attack or open-heart bypass surgery within the last 3 months
  • Your CRT heart device is not working properly due to a technical problem
  • You or your doctor prefer to let your heart's natural electrical system control your heartbeat rather than the device
  • Your overall health means you are not expected to survive for more than 1 year
  • You have other serious health conditions that could interfere with how the trial is run (confirm with trial site)
  • You have dementia, as measured by a short memory and thinking test scoring below 23 out of 30

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jiří Plášek, MD,PhD,FESC, University Hospital Ostrava

Phone: 0042059737

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University Hospital Ostrava
Registry
ClinicalTrials.gov
Start date
1 April 2023
Est. completion
31 December 2028

Where this trial is recruiting

🇨🇿 Czechia

Primary endpoints

Heart failure (HF) events; 36-Item Quality of Life (QoL); Minnesota Living with Heart Failure Questionnaire (MLHFQ); Dose of loop diuretics; NYHA classification

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov