Atrial Fibrillation Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 60 and 80 years old
• People who have been diagnosed with persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own)
• People whose doctor has recommended treatment to restore a normal heart rhythm
• People who have scored between 18 and 25 points on a standard memory and thinking test called the Montreal Cognitive Assessment, which corresponds to mild cognitive impairment
• People who are not under any form of legal guardianship or supervision by another person
• People who are able to understand and agree to follow the requirements of the study
• People who are covered by French national health insurance, either directly or through a third party
• People who have given written consent to take part after receiving full information about the study

Who may not be able to join:

• People who are unable to complete the thinking and memory tests, for example due to hearing loss, difficulty speaking, or a language barrier
• People who have previously had a stroke
• People who have had a sound detected in the neck arteries during examination, or who have a history of severe narrowing of the neck arteries (carotid stenosis)
• People with a known or suspected history of a brain or nerve condition such as Parkinson's disease, Alzheimer's disease, Huntington's disease, or ALS, or a history of bipolar disorder, schizophrenia, severe depression, or a condition called amyloidosis
• People who have previously had a procedure to treat atrial fibrillation by ablation (a treatment that uses energy to destroy small areas of heart tissue causing the irregular rhythm)
• People currently having an ablation procedure for flutter or atrial tachycardia (other types of irregular heart rhythm, not atrial fibrillation)
• People for whom atrial fibrillation ablation is not medically safe, for example due to a blood clot in the heart, severe high blood pressure in the lungs, a mechanical heart valve, or a reason they cannot take blood thinners
• People who cannot safely take anti-arrhythmic medications (medicines used to control heart rhythm) or have a medical reason they cannot have a small heart monitor implanted under the skin
• People whose atrial fibrillation has been present for more than 3 years, or whose heart measurements show the heart's upper left chamber is very enlarged (confirm with trial site for specific measurements)
• People whose life expectancy at the time of enrolment is less than 24 months
• People who are not able to give informed consent to participate
• People in legally protected categories, including minors, people detained by legal or administrative order, adults under legal protection, or people in emergency medical situations
• Women who are pregnant or breastfeeding, and women of childbearing age who are not using an effective form of contraception (such as hormonal methods, barrier methods, an intrauterine device, or surgical procedures such as tubal ligation or hysterectomy)

Important: Always verify eligibility with the trial site directly before applying.