Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting NCT05802329 Sponsor: Ocugen Condition: Retinal Vein Occlusion and Diabetic Macular Oedema
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Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting

NCT05802329
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with either Type 1 or Type 2 Diabetes.
  • People whose reduced vision is mainly caused by diabetic macular oedema (swelling in the central part of the retina caused by diabetes).
  • People whose eye scan results show a specific level of retinal swelling in the central area — the exact measurements differ depending on sex and the type of scanning machine used (confirm with trial site).
  • People whose vision test results fall within a specific range on a standardised eye chart called the ETDRS chart — not too severely reduced, but not near-normal either (confirm with trial site).
  • People whose eyes are clear enough, and who are able to cooperate sufficiently, to allow good-quality retinal photos and scans to be taken.
  • People who have either never had anti-VEGF injections into the eye, or who have had at least 2 anti-VEGF injections close together (less than 7 weeks apart) without the retinal swelling fully resolving — with the most recent injection given at least 6 weeks before the start of the study.

Who may not be able to join:

  • People with any eye condition that blocks a clear view of the retina, such as a significant cataract or bleeding inside the eye.
  • People with high blood pressure that is not well controlled.
  • People with glaucoma that is not well controlled.
  • People who have another eye disease in the eye being studied, beyond the diabetic macular oedema.
  • People who have had steroid injections in or around the eye being studied within the past 3 months.
  • People who have had any eye surgery in the eye being studied within the past 3 months.
  • People whose diabetes is poorly controlled, specifically those with a blood sugar marker (HbA1c) of 10% or higher.
  • People who have a history of the retina detaching in the eye being studied, or other blood vessel diseases affecting the retina in that eye.
  • People who have had a certain type of laser treatment to the retina in the eye being studied within the past 3 months.
  • People who have an inherited retinal disease, or a history of an advanced form of diabetic eye disease called proliferative diabetic retinopathy.
  • People with a moderate-to-severe stage of kidney disease (stage 3b or worse).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Huma Qamar, MD, MPH, CMI, Ocugen

Phone: 845-664-1505

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Ocugen
Registry
ClinicalTrials.gov
Start date
13 January 2024
Est. completion
31 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Study Drug-related adverse events (SDAE); Treatment-emergent adverse events (TEAEs); Serious adverse events (SAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov