Parkinson's Disease Trial, Recruiting NCT05818189 Sponsor: Oregon Health and Science University Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT05818189
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Parkinson's Disease by a specialist doctor, confirmed using a standard set of criteria that includes slowness of movement plus at least one of the following: tremor at rest, muscle stiffness, or balance problems.
  • You do not have any significant bone, joint, or nerve problems (other than Parkinson's) that could seriously affect your balance or walking.
  • You are able to understand and follow instructions, and able to give your own consent to take part.
  • Your Parkinson's is at a moderate stage — not very mild and not severely advanced (specifically rated at Hoehn & Yahr levels II or III, confirm with trial site if unsure what stage you are).

Who may not be able to join:

  • You have severe involuntary movements (such as uncontrolled writhing or jerking) caused by Parkinson's medication that could interfere with brain activity monitoring equipment.
  • You have a significant bone or joint condition, another nervous system or brain disorder, epilepsy, stroke, serious head injury, inner ear/balance problem, or serious active illness (other than Parkinson's) that noticeably affects how you walk or turn.
  • You score below 21 on a standard memory and thinking test called the MoCA, or you have dementia that would prevent you from giving consent or following the study steps.
  • You are unable to stand or walk for 2 minutes on your own without using a walking aid such as a cane or walker.
  • You have been diagnosed with a Parkinson's-related condition that is not standard Parkinson's Disease (such as progressive supranuclear palsy, multiple system atrophy, or corticobasal syndrome), have had deep brain stimulation electrodes implanted, may have Parkinson's caused by blood vessel problems, or are currently taking certain medications that block dopamine or affect brain chemical activity (confirm with trial site which specific medications apply).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Martina Mancini, PhD, Oregon Health and Science University

Phone: 503-913-3691

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
15 January 2025
Est. completion
1 October 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Prefrontal cortex activity; Parietal cortex activity; Stride time variability; Local Dynamic Stability; Turn duration; Turn jerk

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov