Phase 2 Pancreatic Cancer Trial, Recruiting NCT05841420 Sponsor: Morten Ladekarl Condition: Pancreatic Cancer
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Phase 2 Pancreatic Cancer Trial, Recruiting

NCT05841420
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older
  • People who have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample
  • People whose pancreatic cancer cannot be surgically removed, either because it has spread to nearby areas or to other parts of the body
  • People who are not suitable for, or cannot tolerate, a full-strength combination chemotherapy treatment
  • People who are suitable for either full-dose gemcitabine (a chemotherapy drug) alone, or a lower-dose combination chemotherapy
  • People whose general health and ability to carry out daily activities meets a certain minimum level (confirm with trial site)
  • People who have a tumour that can be measured on scans, or one that cannot be measured but is still detectable
  • People whose blood counts (infection-fighting cells and platelets) are at adequate levels within 2 weeks before joining
  • People whose liver and kidney function are within acceptable ranges within 2 weeks before joining
  • People where any side effects from previous chemotherapy, including nerve-related effects, have largely resolved
  • People who have given written and verbal agreement to take part, in line with local ethics requirements
  • People who are capable of having children must be using appropriate contraception

Who may not be able to join:

  • People whose cancer may be suitable for chemotherapy aimed at shrinking the tumour before surgery, local destruction, or radiation treatment
  • People who have already had chemotherapy for their pancreatic cancer (though people who had chemotherapy after surgery and whose cancer came back more than 6 months after finishing that treatment may still be considered eligible)
  • People who have another active cancer that is not being treated with curative intent, in addition to their pancreatic cancer
  • People who are currently receiving any other cancer treatment
  • People who are pregnant or breastfeeding
  • People who clearly intend to leave the trial if not assigned to their preferred treatment group, or who cannot attend regular follow-up appointments due to personal, social, or location-related reasons
  • People with any other medical condition or treatment that, in the treating doctor's judgement, could put them at risk or affect how the trial runs
  • People with a known allergy or intolerance to any of the drugs used in this trial: gemcitabine, S-1, or nab-paclitaxel

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Morten Ladekarl, Professor, Aalborg Universitets Hospital, Department of Oncology

Phone: 0045+61399326

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Morten Ladekarl
Registry
ClinicalTrials.gov
Start date
12 June 2023
Est. completion
1 June 2025

Where this trial is recruiting

🇩🇰 Denmark

Primary endpoints

PFS (Progression Free Survival)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov