Phase 4 Depression and Anxiety Trial, Recruiting NCT05851898 Sponsor: Wake Forest University Health Sciences Condition: Depression and Anxiety
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Phase 4 Depression and Anxiety Trial, Recruiting

NCT05851898
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 65 years old or older
  • You have a broken bone in your leg or foot area (lower body) caused by a fragility fracture (a break that happened more easily than expected, often due to weaker bones) and had surgery to treat it

Who may not be able to join:

  • You have injuries to multiple parts of your body at the same time (polytrauma)
  • Your bone fracture was caused by an underlying disease, such as a tumor or cancer spreading to the bone
  • You are currently receiving hospice (end-of-life comfort) care
  • You have previously been diagnosed with a psychiatric (mental health) disorder
  • You have previously been diagnosed with dementia
  • You are currently taking antidepressant medications known as SSRIs or SNRIs (such as fluoxetine, sertraline, or venlafaxine)
  • You are currently taking medications used to stabilize mood (such as those used for bipolar disorder)
  • You are unable to give your own informed consent to participate in the study (a legal representative cannot provide consent on your behalf)
  • You have a pre-existing condition that seriously limits your life expectancy, such as cancer (confirm with trial site for other qualifying conditions)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Rachel Seymour, PhD, Wake Forest University Health Sciences

Phone: 704-403-4980

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
8 April 2024
Est. completion
1 December 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Geriatric Depression Scale (Short Form) Scores; Geriatric Depression Scale (Short Form) Scores

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov