Myeloma Trial, Recruiting NCT05866757 Sponsor: University College Cork Condition: Myeloma
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Myeloma Trial, Recruiting

NCT05866757
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older.
  • People who have been diagnosed with multiple myeloma and have only received one line of treatment (this includes induction therapy, consolidation therapy, a stem cell transplant, and maintenance — all counted together as one line; switching from one maintenance drug to another due to side effects is also counted as one line).
  • People who have been on maintenance therapy (ongoing treatment to keep the disease in remission) for at least 2 years.
  • People who stopped maintenance therapy before 2 years because of side effects, but who also achieved a sustained deep remission with no detectable cancer remaining (known as MRD-negative complete remission) — these people may also be considered (confirm with trial site).
  • People who are able to understand and willing to sign a consent form, and who agree to follow the study schedule, knowing they are free to withdraw at any time without it affecting their future medical care.

Who may not be able to join:

  • People who have received more than one line of treatment for their myeloma, or who have not completed two years of maintenance therapy (unless maintenance was stopped due to side effects and deep remission with no detectable cancer has been achieved).
  • People who have a related but different plasma cell disorder, such as Waldenström's macroglobulinemia, AL amyloidosis, or POEMS syndrome, rather than multiple myeloma.
  • People who have previously had an organ transplant, or who have a condition that requires them to take medication to suppress their immune system.
  • People who have previously had a donor (allogeneic) stem cell or bone marrow transplant.
  • People who have received an experimental treatment that did not include maintenance therapy as part of the treatment plan.
  • People who are unable to sign a consent form.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 00353214922000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University College Cork
Registry
ClinicalTrials.gov
Start date
28 August 2023
Est. completion
1 July 2027

Where this trial is recruiting

🇮🇪 Ireland

Primary endpoints

Number of participants that remain in sustained MRD negative remission by NGF in the bone marrow at 12 months after discontinuation of maintenance therapy.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov