Phase 3 Atrial Fibrillation Trial, Recruiting NCT05890664 Sponsor: University Hospital, Basel, Switzerland Condition: Atrial Fibrillation
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Phase 3 Atrial Fibrillation Trial, Recruiting

NCT05890664
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are over 18 years of age
  • People who have been diagnosed with atrial fibrillation (an irregular heart rhythm) confirmed by a heart tracing (ECG) before their cardioversion procedure
  • People whose heart was successfully returned to a normal rhythm during cardioversion, and stayed in normal rhythm for at least 30 minutes afterwards
  • People who are able to give written consent to participate

Who may not be able to join:

  • People whose heart did not return to normal rhythm during cardioversion, or whose irregular rhythm came back within 30 minutes of the procedure
  • People who had a heart rhythm problem other than atrial fibrillation before their cardioversion
  • People who had a pulmonary vein isolation procedure (a type of heart procedure) within the 3 months before cardioversion, or who have one planned within 3 months after
  • People who have a known intolerance or allergic reaction to the medication Colchicine
  • People who are already taking Colchicine for another medical reason
  • People who are currently taking certain medications that strongly affect how the body processes drugs, including clarithromycin, erythromycin, telithromycin, cyclosporine, ketoconazole, or itraconazole
  • People who have serious digestive system problems, such as severe stomach inflammation or persistent diarrhoea
  • People who have a significant liver condition that is causing noticeable symptoms
  • People who have severe kidney disease (confirm with trial site for specific kidney function measurement)
  • People who have a significant disorder affecting their blood cells (for example, certain bone marrow conditions)
  • People who have a seriously weakened immune system, for example due to an organ transplant or certain autoimmune conditions
  • Women who are pregnant, breastfeeding, or who could become pregnant and are not using a highly effective form of contraception
  • People who are not expected to live longer than one year

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Philipp Krisai, PD Dr. med., University Hospital, Basel, Switzerland

Phone: +41 61 265 25 25

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University Hospital, Basel, Switzerland
Registry
ClinicalTrials.gov
Start date
14 April 2024
Est. completion
1 March 2027

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Number of atrial fibrillation (AF) recurrence

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov