Phase 1 Myeloma Trial, Recruiting NCT05892393 Sponsor: Robert Flavell, MD, PhD Condition: Myeloma
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Phase 1 Myeloma Trial, Recruiting

NCT05892393
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with multiple myeloma, confirmed through a laboratory test of tissue or cell samples, using recognised international diagnostic standards
  • People who have at least one area of myeloma activity detected on a specialised imaging scan (PET/CT or PET/MRI), where the affected area shows higher activity than the liver on the scan
  • People aged 18 years or older
  • People whose liver function blood test results (bilirubin, AST, and ALT) are within acceptable ranges as determined by the trial laboratory
  • People whose kidneys are functioning at or above a minimum level, based on a standard calculation or blood test result
  • People who are able to understand and are willing to sign a written consent form

Who may not be able to join:

  • People who have any health condition that, in the lead investigator's judgement, could affect their ability to follow the study procedures or raise safety concerns
  • People who are currently pregnant or breastfeeding/chestfeeding
  • People who are able to become pregnant and do not have a negative pregnancy test (urine or blood) within 72 hours before receiving the study imaging agent — if the urine test result is unclear or positive, a blood test is required, and a positive blood test result would mean the person cannot join
  • People who are able to become pregnant are considered in this category unless records confirm they have not had a menstrual period for 12 or more consecutive months (with no other medical explanation), or they have had a surgical procedure to remove the uterus and/or both ovaries
  • People who are pregnant or breastfeeding/chestfeeding are excluded because the study imaging agent may carry unknown risks to an unborn baby or nursing child

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Robert Flavell, MD, PhD, University of California, San Francisco

Phone: (415) 514-8987

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Robert Flavell, MD, PhD
Registry
ClinicalTrials.gov
Start date
16 June 2023
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Sensitivity of metastatic lesion; Median maximum standardized uptake value (SUVmax); Median Standardized Uptake Value averaged across lesions (SUVmax-avg)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov