Phase 4 Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are scheduled to have a vasectomy
- People aged between 21 and 85 years
- People who are considered suitable to breathe a nitrous oxide and oxygen gas mixture (confirm with trial site)
- People who have access to an email address and a computer
Who may not be able to join:
- People who have facial hair around the mouth area that would prevent a gas mask from fitting properly
- People with a cognitive impairment that would make it difficult to answer survey questions
- People who plan to use benzodiazepines (sedatives) or opioids (strong painkillers) on an as-needed basis specifically for their vasectomy
- People who have had inner ear, weight-loss (bariatric), or eye surgery within the last 2 weeks
- People who currently have emphysematous blebs (damaged air pockets in the lungs) (confirm with trial site)
- People with a severe Vitamin B12 deficiency
- People who have received the chemotherapy drug bleomycin within the past year
- People who have had a heart attack within the past year
- People who have had a stroke within the past year
- People with Class III or higher heart failure (a more advanced stage of heart failure) (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Heidi Rayala, MD, PhD, Beth Israel Deaconess Medical Center
Phone: 617-667-3739
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Procedural pain assessed by the Visual Analog Scale for Pain (VAS-P)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.