Phase 1 Parkinson's Disease Trial, Recruiting NCT05901818 Sponsor: Xuanwu Hospital, Beijing Condition: Parkinson's Disease
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Phase 1 Parkinson's Disease Trial, Recruiting

NCT05901818
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 30 and 85 years old (male or female)
  • You have been officially diagnosed with Parkinson's disease using standard medical diagnostic guidelines
  • You have had Parkinson's disease for more than 3 years
  • Your Parkinson's symptoms are at a moderate or lower level of severity when your medication is working (confirm with trial site)
  • Your Parkinson's symptoms improve significantly (by more than 30%) when you take levodopa medication

Who may not be able to join:

  • You have a type of Parkinson's-like condition that is not standard Parkinson's disease, or your Parkinson's-like symptoms are caused by another condition
  • You have another condition affecting your brain or nervous system
  • You have another serious illness affecting your overall health or organ function
  • You have a severe mental health condition
  • You are currently taking hormone therapy or certain powerful drugs that affect the immune system, and you are unable to stop taking them during the trial
  • You have memory or thinking difficulties (based on a standard cognitive test score below 24)
  • You experience severe uncontrolled involuntary movements related to your Parkinson's medication (confirm with trial site)
  • You have previously had brain surgery
  • You regularly take blood-thinning medication long-term
  • A brain scan has shown abnormalities that could interfere with surgery or the study's follow-up tests
  • You are unable to have an MRI scan or a specific type of brain imaging scan called an AV133 PET scan
  • You are pregnant or planning to become pregnant
  • The trial doctors have determined for any other reason that participation would not be appropriate for you

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Xuanwu Hospital, Beijing
Registry
ClinicalTrials.gov
Start date
13 June 2023
Est. completion
31 December 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Assessment of changes during the medication "off" time in Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), part III, in comparison with baseline values.; Incidence and severity of transplant-related adverse events.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov