Hypertension Trial, Recruiting NCT05934383 Sponsor: Erasmus Medical Center Condition: Hypertension
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Hypertension Trial, Recruiting

NCT05934383
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older
  • People who received a kidney transplant at least 12 months ago and have been on a stable anti-rejection medication routine
  • People whose kidneys are filtering at a sufficient level (a blood test result called eGFR of 40 or above) (confirm with trial site)
  • People whose blood pressure is high, both when measured in a clinic and when measured over a full 24-hour period using a portable monitor
  • People who have been taking at least two different types of blood pressure medication, including a water pill (diuretic), for at least three months without changes — or who have a documented reason why three types of blood pressure medication cannot be tolerated — and whose blood pressure medication routine is not expected to change in the next three months
  • People who are willing and able to sign a written consent form

Who may not be able to join:

  • People whose natural (original) kidney arteries are not suitable for the procedure, including those who have previously had a stent or balloon procedure in the kidney arteries, a previous kidney nerve-blocking procedure, kidney tumours, kidney artery measurements outside a certain range, a specific artery wall condition called fibromuscular dysplasia, a bulge in the kidney artery (aneurysm), or a significant narrowing of the kidney artery (confirm with trial site)
  • People who have had a second kidney transplant and still have a remaining first transplant kidney, or who no longer have their original kidneys at all
  • People who have only one natural (original) kidney
  • People who have had a serious allergic reaction to contrast dye used in scans, or whose kidneys have been damaged by it in the past
  • People who have a narrowing in the arteries in the groin or hip area that would prevent the procedure's catheter from being inserted
  • People who have a treatable underlying cause of their high blood pressure that has not yet been addressed
  • People who are pregnant
  • People whose life expectancy is estimated at less than one year, based on the treating doctor's assessment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +31107040704

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Erasmus Medical Center
Registry
ClinicalTrials.gov
Start date
4 September 2023
Est. completion
1 January 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Efficacy: change in mean 24-hour ambulatory systolic blood pressure; Safety: occurrence of the composite endpoint

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov