Colorectal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed (confirmed by lab testing of tissue or cells) with a moderate or poorly differentiated cancer of the appendix or colon/rectum that was initially considered treatable with surgery.
• People whose cancer has spread to the lining of the abdomen (peritoneal disease) that can be seen on a scan or during a keyhole surgery procedure.
• People aged 18 or older.
• People who are relatively physically active and able to carry out everyday tasks with minimal limitations (confirm with trial site regarding specific fitness score).
• People whose blood counts and organ function (including liver and kidneys) meet specific minimum health levels as determined by blood tests (confirm with trial site for exact values).
• People with a chronic hepatitis B infection whose virus levels are undetectable while on treatment for it.
• People who previously had hepatitis C and have been successfully treated and cured, or who are currently being treated and have undetectable virus levels.
• People who have had another cancer in the past or at the same time, as long as that cancer or its treatment is unlikely to interfere with this study (confirm with trial site).
• People with a known history of heart disease or past treatment with heart-affecting medicines, provided a doctor's assessment rates their heart function at a certain acceptable level (confirm with trial site).
• People living with HIV who are on effective treatment and have had undetectable virus levels within the past 6 months.
• People with an estimated life expectancy of more than 4 months.
• People who agree to use effective contraception throughout the study and for a specified period after, as the chemotherapy medicines used can harm an unborn baby — this applies to women who could become pregnant and to men.
• People who are able to understand the study and are willing to sign a consent form.
• Both English-speaking and non-English-speaking people are welcome.

Who may not be able to join:

• People who are still experiencing significant side effects (above a mild level) from a previous cancer treatment, except for hair loss.
• People who are currently taking part in another clinical trial involving an experimental treatment.
• People whose cancer has spread to the brain, liver, or lungs (confirm with trial site, as this may be assessed case by case).
• People with other serious illnesses that are not well controlled.
• People with a psychiatric illness or personal circumstances that would make it difficult to follow the study requirements.
• People who are currently pregnant or breastfeeding.
• People who have had major surgery within the past 4 weeks and have not yet sufficiently recovered from it.
• People who have previously experienced serious (grade 3 or 4) chemotherapy side effects that were severe enough to require a break in treatment of more than 6 weeks.
• People for whom the treating doctor believes participation would not be in their best interest, or whose health history or test results may make the study results harder to interpret.

Important: Always verify eligibility with the trial site directly before applying.