Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older.
- You have been diagnosed with a long-lasting or ongoing irregular heartbeat (called persistent or long-standing persistent atrial fibrillation), confirmed by your medical records or a heart tracing test (ECG).
- Your doctor has calculated your stroke risk score (called CHA2DS2-VASc) to be 2 or higher if you are male, or 3 or higher if you are female.
- You are willing to undergo a keyhole surgical procedure (thoracoscopic) to close off a small pouch in the heart called the left atrial appendage (LAA).
Who may not be able to join:
- You are planning to have an electric shock treatment (cardioversion) or a procedure to correct your heart rhythm (ablation).
- You have another heart condition that requires surgery.
- You have had a stroke or a blood clot-related event from the heart within the last 30 days.
- You have had a serious bleeding episode within the last 30 days.
- You are unable to take blood-thinning medications for medical reasons.
- You currently have a blood clot inside your heart.
- Your heart's pumping strength is significantly reduced (confirm with trial site).
- You have an active infection in your body, or an infection affecting your heart lining or the sac around your heart.
- You have severe liver disease (such as hepatitis or cirrhosis) or abnormal liver blood test results above a certain level.
- You have severe kidney problems where your kidneys are not filtering blood well enough.
- You need to take blood-thinning tablets long-term for another medical condition.
- You have active plaque build-up in your main large artery (the aorta).
- You have had a heart attack or serious heart event within the last 3 months.
- You have significant narrowing of the arteries leading to your brain (carotid arteries) that is causing symptoms.
- You need to take two different anti-clotting medications at the same time.
- You have had previous surgery on your heart or left lung.
- You have severe scarring or adhesions around your left lung or the sac around your heart.
- You are currently pregnant or breastfeeding.
- You have a known allergy to metal.
- You have a serious illness where your life expectancy is less than 2 years.
- You are currently taking part in another clinical trial.
- You do not wish to participate in this study.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Zhe Zheng, MD,PhD, Chinese Academy of Medical Sciences, Fuwai Hospital
Phone: +86-010-88396051
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Rate of composite endpoint
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.