Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06045767 Sponsor: Ari Raphael Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06045767
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • The person joining (or their legal representative, if applicable) must be willing and able to give written consent to take part in the trial.
  • The person must have measurable disease according to a standard measurement system called RECIST 1.1, including lesions in previously treated areas if those lesions have shown signs of growth.
  • A tissue sample from the tumour must be available — either stored from a previous procedure or newly collected — from an area that has not been treated with radiation.
  • The person must have a general health and activity level rated 0 or 1 on a standard scale (meaning fully active or able to carry out light work), as assessed by their doctor.
  • The person must have adequately functioning major organs such as the liver, kidneys, and blood cells (confirm with trial site for specific thresholds).

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who are pregnant or breastfeeding.
  • People whose cancer has a specific known genetic change that can be targeted by other existing treatments.
  • People who have previously received certain types of immunotherapy drugs that work on immune system checkpoints (such as anti-PD-1, anti-PD-L1, or anti-PD-L2 agents, or similar treatments).
  • People who have previously received any systemic (whole-body) cancer treatment for cancer that has spread to other parts of the body.
  • People who have received radiation therapy within 2 weeks before the start of the trial treatment.
  • People who have had major surgery within 14 days before joining the trial.
  • People who have a condition affecting their immune system, or who are currently taking ongoing steroid medication through the whole body (such as tablets or injections, not creams).
  • People who have another cancer that is currently getting worse or has needed active treatment within the past 3 years.
  • People with active cancer spread to the brain or the lining around the brain — though people with previously treated or symptom-free brain spread that has been stable on scans may still be considered.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026

Contact this trial

Principal Investigator: Ari Raphael, M.D, Tel-Aviv University school of medicine

Phone: +972-3-6973082

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Ari Raphael
Registry
ClinicalTrials.gov
Start date
1 June 2024
Est. completion
1 January 2029

Primary endpoints

Objective Response Rate (ORR) per RECIST 1.1 - correlated to TCR repertoire data, such as clonality/diversity.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov