Parkinson's Disease Trial, Recruiting NCT06087926 Sponsor: University of North Carolina, Chapel Hill Condition: Parkinson's Disease
Back to Parkinsons Disease

Parkinson's Disease Trial, Recruiting

NCT06087926
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with idiopathic (no known cause) Parkinson's disease.
  • You have had Parkinson's symptoms for at least 5 years.
  • You are currently taking medication for Parkinson's disease that works on dopamine in the brain.
  • Your Parkinson's medications (and any antidepressants or stimulant medications) have stayed the same for at least 4 weeks before the first study visit, and you are able to keep them stable throughout the study.
  • You are willing and able to sign a consent form agreeing to take part in the study.
  • You are able to understand and complete the consent process in English.
  • If you are female, you have not had a menstrual period in over 12 months, or you agree to use an effective form of contraception during the study.

Who may not be able to join:

  • You are not able to give informed consent to take part.
  • You are unable to complete a specific effort-based task used in the study (this is checked at an early session).
  • You have dementia or significant memory/thinking difficulties (based on a standard cognitive test score).
  • You have a history of epilepsy (seizures) or have had brain surgery.
  • You have severe tremor or involuntary movements that would interfere with brain activity recordings (determined by the study doctor).
  • You have a medical or neurological condition that may be causing Parkinson's-like symptoms for a different reason, such as repeated brain injuries, certain medications, oxygen deprivation to the brain, or significant strokes in a specific brain region.
  • You have another known brain or nervous system condition that could affect the study's brain recordings or treatments.
  • You have any implanted metal devices in your body, such as a pacemaker, deep brain stimulator, nerve stimulator, bladder stimulator, or cochlear implant.
  • You have any medical reason that means you cannot safely receive a brain stimulation technique called TMS, including a history of mania, bipolar disorder, or epilepsy (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Miriam Sklerov, MD, University of North Carolina, Chapel Hill

Phone: 919-445-0979

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 May 2024
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in goal-directed behavior after transcranial magnetic stimulation (TMS); Change in reward evaluation after transcranial magnetic stimulation (TMS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov