Atrial Fibrillation Trial, Recruiting NCT06125925 Sponsor: The First Affiliated Hospital with Nanjing Medical University Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT06125925
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have atrial fibrillation (an irregular heartbeat) that comes and goes or is ongoing, and it causes symptoms
  • Your doctor has calculated a stroke risk score (called CHA₂DS₂-VASc) of 2 or higher
  • You have been diagnosed with a type of heart failure where the heart pumps normally but doesn't relax properly (sometimes called HFpEF), which includes all of the following:
  • You have noticeable to severe symptoms from your heart condition (NYHA Class II–IV)
  • Your heart's pumping strength is 50% or more (confirmed by a heart scan)
  • A specific protein in your blood (NT-proBNP) is above a certain level, depending on your heart rhythm at the time of testing (confirm with trial site for exact values)
  • An ultrasound of your heart shows that it has difficulty relaxing and filling properly
  • You are willing and able to sign a consent form agreeing to take part

Who may not be able to join:

  • You have a non-heart-related illness that means you are not expected to live for more than 2 years
  • Your atrial fibrillation is caused by a treatable condition, such as an overactive thyroid or low potassium levels
  • You have previously had a procedure to treat atrial fibrillation using heat energy (ablation)
  • The upper chamber of your heart (left atrium) is larger than 55 mm
  • Your heart failure is caused by certain specific heart conditions, such as inherited thickened heart muscle, certain rare heart muscle diseases, or problems with the sac around the heart (confirm with trial site for full list)
  • You have previously had a heart transplant, have a complex heart defect present from birth, or have rheumatic heart disease
  • You have any medical reason why you cannot safely have an ablation procedure, take anti-arrhythmia medications, or take blood thinners
  • You had a heart attack, heart surgery, a heart artery procedure, or a stroke within the 12 weeks before joining the trial
  • You have severe liver or kidney problems
  • Your body mass index (BMI) is above 50
  • You are currently pregnant or breastfeeding
  • You are already taking part in another clinical study
  • Your doctor feels there is any other reason you may not be able to complete the study safely

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +86-18094226858

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
6 November 2023
Est. completion
1 November 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Composite endpoint of worsening heart failure requiring unplanned hospitalizations or urgent visits, and cardiovascular death (Time-to-first event analysis)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov