Peripheral Neuropathy Trial, Recruiting NCT06129890 Sponsor: Centre Hospitalier Universitaire de Saint Etienne Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT06129890
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have neuropathic pain (nerve pain) that is either central (from the brain or spinal cord) or peripheral (from nerves in the body).
  • Your pain has been ongoing for more than 6 months and rates at least 4 out of 10 in severity.
  • Your pain is present most days — at least 4 days per week.
  • Your pain has not been fully relieved by the standard first- or second-line medications recommended for nerve pain.
  • You have been on a stable pain medication routine for at least one month, with no new treatments or dose changes, and this is expected to stay the same throughout the study.
  • You have been diagnosed with a depressive episode according to recognised psychiatric guidelines (DSM V criteria).
  • A neurologist has recommended you for a type of brain stimulation treatment called motor cortex rTMS.
  • You are able to attend all appointments for the full duration of the study.
  • You have been fully informed about the study and have signed a consent form with the research team.
  • You are covered by a social security (health insurance) scheme.

Who may not be able to join:

  • You are involved in an industrial accident claim or ongoing legal dispute related to your condition.
  • You have a reason why rTMS or MRI cannot be safely used for you — for example: you have had electroconvulsive therapy in the past month; you have epilepsy or a history of it; you have had a serious head injury; you have had brain surgery; you have high pressure in the skull; you have a metal clip in the brain, a pacemaker, an insulin pump, or certain metal implants; you are pregnant or breastfeeding; or you have severe claustrophobia.
  • You have a problem with misusing drugs or psychoactive substances.
  • Your nerve pain is caused by a condition that is still progressing, such as HIV, cancer, or a systemic disease.
  • You have another type of pain that is more severe than the nerve pain being studied.
  • You are unable to understand the information given about the study and what taking part involves.
  • You are unwilling or unable to stop taking certain treatments that are not allowed during the study.
  • You have taken part in another clinical drug trial within the 30 days before joining this study.
  • You are subject to a legal protection order, such as guardianship or curatorship (confirm with trial site).
  • You are under 18 years of age.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: (0)4 77 12 78 05

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Registry
ClinicalTrials.gov
Start date
26 April 2024
Est. completion
1 September 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Comparison of pain relief rates between the two stimulation targets (M1 and DLPFC)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov