Phase 2 Myeloma Trial, Recruiting NCT06140524 Sponsor: Regeneron Pharmaceuticals Condition: Myeloma
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Phase 2 Myeloma Trial, Recruiting

NCT06140524
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with either high-risk MGUS (an early blood condition where abnormal proteins are found) or a lower-risk form of smoldering multiple myeloma (a pre-cancer condition with no symptoms yet), as defined by the trial guidelines
  • You are generally able to carry out daily activities with no or minimal limitations (confirm with trial site for exact definition)
  • Your blood counts and liver function are within an acceptable range, as set out by the trial guidelines (confirm with trial site for exact values)
  • Your kidneys are working at a sufficient level, measured by a standard kidney function test

Who may not be able to join:

  • You have been diagnosed with a higher-risk form of smoldering multiple myeloma, as defined by the trial guidelines
  • You are showing signs that your condition has progressed toward active multiple myeloma, as described in the trial guidelines (confirm with trial site)
  • You have been diagnosed with certain related blood or bone marrow conditions, including light-chain amyloidosis, Waldenström macroglobulinemia, solitary plasmacytoma, or active (symptomatic) multiple myeloma
  • You have had a serious heart or blood vessel problem within the 3 months before joining the trial (confirm with trial site for exact details)
  • You have had an infection serious enough to require a hospital stay or treatment through an IV drip within 28 days before starting the trial medication
  • You have HIV, Hepatitis B, or Hepatitis C that is not well controlled, or any other ongoing or unexplained infection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Clinical Trial Management, Regeneron Pharmaceuticals

Phone: 844-734-6643

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Regeneron Pharmaceuticals
Registry
ClinicalTrials.gov
Start date
16 September 2024
Est. completion
18 May 2032

Where this trial is recruiting

🇧🇪 Belgium 🇫🇷 France 🇮🇪 Ireland 🇮🇹 Italy 🇵🇱 Poland 🇪🇸 Spain 🇺🇸 United States

Primary endpoints

Frequency of Adverse Events Interest (AEI) during the safety observation period; Frequency of Treatment-Emergent Adverse Event (TEAEs) during the safety observation period; Severity of TEAEs during the safety observation period; Achievement of Complete Response (CR) as determined by the investigator

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov