Phase 2 Pancreatic Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have suspected pancreatic cancer that doctors believe can be removed with surgery
- You are being considered for surgery with the goal of curing the cancer
- You are willing and able to sign a consent form agreeing to take part
- You are at least 18 years old
- If you are a woman who could become pregnant, you must be willing to use a reliable form of contraception for the entire duration of the trial
Who may not be able to join:
- You have chronically low blood pressure (below certain levels depending on your sex)
- You have a very slow heart rate (fewer than 50 beats per minute)
- You have asthma or chronic obstructive pulmonary disease (a long-term lung condition)
- Your heart's pumping function is significantly reduced (confirm with trial site)
- Your kidneys are not working well enough (confirm with trial site)
- You have long-term liver problems, such as hepatitis, fatty liver disease, or cirrhosis
- You have a heart condition caused by lung disease (called cor pulmonale)
- You are currently in cardiogenic shock (when the heart suddenly cannot pump enough blood)
- You have serious problems with blood circulation in your limbs
- You have a condition where your blood is too acidic (metabolic acidosis)
- You have a known allergy to propranolol or any of its ingredients
- You have an untreated tumour called a pheochromocytoma
- You have a history of a type of chest pain called Prinzmetal's angina
- You have a history of certain heart rhythm problems (sick sinus syndrome or heart block)
- You have previously had a stroke or any other major heart or blood vessel event
- You have previously received chemotherapy or radiation treatment for your suspected pancreatic cancer
- You have taken propranolol or any other beta-blocker medication in the past 3 months
- You have taken anti-anxiety medications, calcium channel blockers, or certain heart/lung medications in the past 3 months
- Your doctor considers you too frail or otherwise unsuitable for the trial
- Your tissue sample (if already taken) shows the growth is not cancerous
- You have a psychiatric illness, dementia, or are unable to read or speak sufficient Danish, which would prevent you from giving fully informed consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ismail Gögenur, Professor, Center for Surgical Science, Zealand University Hospital
Phone: +4547323181
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Preoperative anxiety; Preoperative anxiety and depression; Preoperative quality of life; Density and subtypes of tumor-infiltrating lymphocytes in the tumor microenvironment.; Desmoplasia in the tumor microenvironment.; Neural markers in the tumor microenvironment.; Adrenergic receptor (ADRB1&ADRB2) expression in the tumor microenvironment.; Spatial distribution of immune cells in the tumor microenvironment.; Immune cells and subtypes in blood samples; Circulating tumor cells before and after intervention in blood samples.; RNA-level gene expression in blood samples.; Heart rate variability in...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.