Phase 1 Myeloma Trial, Recruiting NCT06153251 Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Condition: Myeloma
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Phase 1 Myeloma Trial, Recruiting

NCT06153251
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with multiple myeloma that has come back (relapsed) or stopped responding to treatment (refractory).
  • People whose myeloma showed signs of getting worse either during or within 12 months of finishing their most recent myeloma treatment (measured from the last dose of that treatment).
  • People who have previously received at least two specific types of myeloma treatment: a proteasome inhibitor and an immunomodulatory agent (confirm with trial site for which part of the trial applies).
  • People who have a good general level of daily functioning, rated 0 or 1 on a standard medical scale where 0 means fully active and 1 means able to carry out light activities (confirm with trial site).
  • People whose major organs such as the kidneys, liver, and heart are working well enough to meet the trial's requirements (confirm with trial site for specific thresholds).

Who may not be able to join:

  • People who have, or have previously had, myeloma that has spread to the brain or spinal cord.
  • People who have, or have previously had, certain related blood or protein disorders, including plasma cell leukemia, Waldenström's macroglobulinemia, POEMS syndrome, or a significant form of amyloidosis.
  • People who have a history of, or are currently experiencing, significant brain or nervous system conditions such as seizures, stroke, severe brain injury, dementia, Parkinson's disease, cerebellar disease, speech problems (aphasia), or active psychosis.
  • There are additional criteria set out in the trial protocol that may also affect whether someone is able to join (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Registry
ClinicalTrials.gov
Start date
23 January 2024
Est. completion
2 May 2030

Where this trial is recruiting

🇫🇷 France 🇩🇪 Germany 🇪🇸 Spain 🇺🇸 United States

Primary endpoints

Number of participants with treatment-emergent adverse events (AEs); Number of participants with serious adverse events (SAEs); Number of participants with AEs leading to discontinuation; Number of participants with AEs leading to death; Number of participants with dose-limiting toxicities (DLTs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov