Type 1 Diabetes Trial, Recruiting NCT06158503 Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Condition: Type 1 Diabetes
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Type 1 Diabetes Trial, Recruiting

NCT06158503
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • You have been diagnosed with Type 1 diabetes or a slow-developing form of adult autoimmune diabetes (called LADA) for at least one year
  • Your recent average blood sugar level (HbA1c) is above 8.0%, and your blood sugar levels vary a lot throughout the day as measured by a continuous glucose monitor (CGM)
  • You are planning to start using one of the automated insulin delivery (AID) systems that are already available on the market
  • You plan to use the fully automated ("closed-loop") mode of the device
  • You are willing to share your CGM data with the research team during the study

Who may not be able to join:

  • You are a woman who is pregnant, gave birth, or was breastfeeding less than 6 months before the study starts, or who plans to become pregnant during the study
  • You have certain health conditions that affect bone health, such as advanced kidney disease, liver disease, celiac disease or other gut absorption problems, a history of organ transplant, active cancer, rheumatoid arthritis, or certain hormone disorders (confirm with trial site)
  • You are expected to change your CGM sensor, insulin pump, or AID system during the study period
  • You expect to need to take acetaminophen (e.g., Tylenol/paracetamol) at doses higher than 1g every 6 hours during the study
  • You are currently taking or plan to take a medication called hydroxyurea
  • You have taken certain medications in the past 12 months that affect bone health, including high-dose steroids, certain breast or prostate cancer treatments, blood thinners, or specific diabetes or osteoporosis medications (confirm with trial site for the full list)
  • You are not able to give your informed consent to participate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Rémi Rabasa-Lhoret, MD, PhD, IRCM

Phone: 514-987-5617

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Registry
ClinicalTrials.gov
Start date
1 February 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Bone remodeling improvement

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov