Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06182761 Sponsor: Shanghai Zhongshan Hospital Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06182761
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are able to give informed consent and agree to follow the rules and requirements of the trial.
  • People who have been diagnosed with a type of lung cancer called non-squamous non-small cell lung cancer (NSCLC) that has spread locally or to other parts of the body.
  • People whose lung cancer has a specific gene change (mutation) — called 19del, L858R, or T790M — confirmed by an approved laboratory.
  • People who cannot tolerate, have refused, or are not suitable for standard chemotherapy.
  • People whose cancer has stopped responding to a type of targeted therapy called EGFR-TKI, or who could not tolerate it; those with the T790M mutation must have already been treated with osimertinib or another third-generation EGFR-TKI.
  • People with a general health/activity level rated 0 or 1 on the World Health Organization scale (meaning largely able to carry out normal daily activities).
  • People with a life expectancy of more than 12 weeks at the time of starting the trial.
  • People who have at least one measurable area of cancer that can be monitored.
  • Women of childbearing potential who have a negative pregnancy test before starting and who are using highly effective contraception, or women with confirmed evidence that they cannot become pregnant.
  • Men who are willing to use barrier contraception (such as condoms) during the trial.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose cancer has certain other specific gene changes, including RET rearrangement, BRAF V600E mutation, NTRK fusion, MET ex14 skip mutation, or MET amplification (confirm with trial site for exact testing details).
  • People who have had another active cancer in the past 2 years.
  • People who have had major surgery within 4 weeks before starting the trial.
  • People who still have unresolved side effects from a previous cancer treatment.
  • People with a past or current history of a lung condition called interstitial lung disease (ILD) or pneumonitis, including types caused by drugs or radiation that needed steroid treatment.
  • People with severe or uncontrolled serious illnesses.
  • People with certain heart-related conditions, including an abnormal heart rhythm measurement on an ECG, other important heart rhythm or electrical problems, or factors that increase the risk of heart rhythm complications (confirm with trial site for specific details).
  • People with ongoing nausea and vomiting that cannot be managed, chronic gut/digestive diseases, difficulty swallowing, or who have had significant bowel surgery that could affect how the trial medications are absorbed.
  • People with severe allergies to either of the trial medications, Sunvozertinib or Anlotinib.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026

GP referral letter

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Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 January 2024
Est. completion
1 January 2026

This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.

Primary endpoints

ORR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov