Phase 4 Atrial Fibrillation Trial, Recruiting NCT06184633 Sponsor: Rijnstate Hospital Condition: Atrial Fibrillation
Back to Atrial Fibrillation

Phase 4 Atrial Fibrillation Trial, Recruiting

NCT06184633
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been recently diagnosed with persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own) that is causing symptoms, diagnosed no more than 6 months before joining the trial
  • People aged 18 or older
  • People with a body mass index (BMI) of 30 or above, OR a BMI of 27 or above combined with at least one weight-related health condition such as high blood pressure, high cholesterol, sleep apnea, or heart disease
  • People who are already scheduled for an electrical cardioversion (a procedure that uses a controlled electric shock to restore normal heart rhythm)
  • People who are willing and able to provide written consent to participate

Who may not be able to join:

  • People with permanent atrial fibrillation (where the irregular heart rhythm is long-lasting and not being treated with cardioversion)
  • People whose atrial fibrillation is caused by another medical condition, such as a thyroid problem, an infection like pneumonia, or recent heart or chest surgery
  • People who are currently taking or have previously taken the heart medication amiodarone
  • People whose blood sugar control test (HbA1c) result was at or above a certain level within the 3 months before joining (confirm with trial site)
  • People with a history of type 1 or type 2 diabetes
  • People who have previously had weight-loss (bariatric) surgery
  • People who have used other weight-loss medications within the 3 months before joining
  • People who have a medical reason not to use a type of medication called a GLP-1 receptor agonist, or who have used one before
  • People with a history of long-term pancreatitis, or who have had a sudden pancreatitis episode within the past 6 months
  • People who have had a heart attack or acute coronary event within the past 6 months
  • People with severe heart valve disease
  • People with significantly reduced kidney function (confirm with trial site)
  • People with severe heart failure that considerably limits physical activity
  • People who have taken part in another clinical drug or device trial within the past 30 days (participation in a registry is allowed)
  • People whose treating doctor considers them unsuitable for the trial for any reason, including a life expectancy of less than 12 months
  • People who are pregnant, breastfeeding, planning to become pregnant, or who are able to become pregnant and are not using a highly effective form of contraception

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Ron Pisters, dr., Rijnstate Hospital

Phone: +31650818296

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Rijnstate Hospital
Registry
ClinicalTrials.gov
Start date
21 July 2024
Est. completion
1 May 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

The primary efficacy clinical endpoint of the trial is assessed at 12 months by a 7 point scale. Only the worst clinical outcome will be retained as the primary efficacy outcome

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov