Type 1 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 6 and 65 years old (any gender).
• You have been diagnosed with type 1 diabetes for at least 1 year, confirmed by at least one positive result for a diabetes-related antibody test.
• Your blood sugar is not well controlled despite using intensive insulin therapy — meaning your HbA1c (a measure of average blood sugar) is 7.5% or higher, or your blood sugar is in a healthy range less than 70% of the time.
• You have had two or more serious low blood sugar episodes (blood sugar dropping very low or being unable to treat it yourself) in the past year, with at least one of these happening in the last 3 months.
• You are willing and able to use the blood sugar monitor provided by the study team, check your blood sugar as instructed, and keep a patient diary.
• If you could become pregnant or father a child, you agree to use a reliable form of birth control during the trial and for at least 90 days after the last dose; women who have not gone through menopause must have a negative pregnancy test before joining.
• You are willing to take part and sign a consent form agreeing to join the trial.

Who may not be able to join:

• You have an uncontrolled infection, such as active tuberculosis, active hepatitis, HIV, or syphilis.
• You have serious problems with a major organ such as your heart, lungs, or brain.
• You have severe diabetes-related complications, such as bleeding in the eyes or diabetic foot.
• Your liver function tests show significantly abnormal results that have not improved with treatment.
• You currently have cancer, or it has been less than 1 year since you were successfully treated for cancer.
• You have serious digestive system problems or immune conditions affecting your gut, or you are unable to take immunosuppressant medications.
• You have a history of smoking, alcohol abuse, or drug misuse.
• You have a serious mental health or psychological condition.
• You have advanced metabolic conditions, such as very high uric acid levels (confirm with trial site).
• You have taken part in another clinical trial within the last 3 months.
• You need long-term high-dose steroid medication (taken by mouth or through a drip) for any condition.
• You are pregnant or currently breastfeeding.
• You have another serious, active, or uncontrolled hormone or immune system condition besides type 1 diabetes.
• The trial doctor decides for any other reason that taking part would not be right for you.

Important: Always verify eligibility with the trial site directly before applying.