Atrial Fibrillation Trial, Recruiting NCT06212791 Sponsor: Virginia Commonwealth University Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT06212791
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 years or older
  • People who have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes on its own)
  • People whose heart is pumping at a normal or near-normal level (a heart pumping function measurement of 50% or above)
  • People who are already scheduled to have a catheter ablation procedure for their atrial fibrillation
  • People who are able to speak, hear, and read English
  • People who are willing and able to give their formal consent to take part in the trial

Who may not be able to join:

  • People whose atrial fibrillation is persistent (does not stop on its own) or permanent
  • People who have previously had an ablation procedure for atrial fibrillation, whether by catheter or surgery
  • People with a significant problem with the heart's natural pacemaker node (sinus node dysfunction)
  • People who have an implanted pacemaker or defibrillator device
  • People who are unable to have or complete a cardiac MRI scan for any reason
  • People who are unable to complete an exercise test for any reason
  • People with significant kidney disease (where kidney filtering function falls below a certain level — confirm with trial site)
  • People with severe thickening of the heart's main pumping chamber wall
  • People with a separate heart muscle condition that is expected to limit their ability to exercise, such as hypertrophic cardiomyopathy, cardiac amyloidosis, or constrictive pericarditis
  • People with high blood pressure in the arteries of the lungs (pulmonary arterial hypertension)
  • People who have previously had heart surgery
  • People who are currently pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Cory Trankle, Virginia Commonwealth University

Phone: 804-628-6234

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
26 December 2024
Est. completion
1 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in LA reservoir function reserve at submaximal exercise after catheter ablation in patients with paroxysmal AF.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov