Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06221462 Sponsor: Ningbo No.2 Hospital Condition: Lung Cancer
Back to Lung Cancer

Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06221462
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have given written consent before the study begins.
  • People aged 18 to 75 years, regardless of sex.
  • People whose non-small cell lung cancer (a type of lung cancer) has been confirmed through a tissue sample test.
  • People who have at least one tumour that can be measured on a scan, according to standard measurement guidelines.
  • People with early-to-mid stage non-small cell lung cancer (stages IB to IIIB) that has not yet been treated and is considered suitable for surgery, based on standard cancer staging.
  • People whose lung cancer does not have certain specific genetic changes (EGFR, ALK, or ROS1 mutations).
  • People who do not have a risk of bleeding.
  • People who have agreed to undergo surgery as part of their treatment.
  • People whose surgeon has confirmed that surgery is appropriate for them.
  • People who are in good general health and able to carry out daily activities, as measured by a standard health scale (ECOG score of 0 or 1).
  • People whose expected survival is more than 6 months.
  • People whose blood, liver, kidney, thyroid, and heart function test results meet the required levels set by the trial (confirm with trial site for specific values).
  • Women of childbearing age who have a negative pregnancy test (urine or blood) taken within 3 days before the first dose of the study treatment.
  • People who are at risk of pregnancy (both male and female) and who use highly effective contraception throughout the treatment period and for 120 days after the last dose of the study treatment.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have been diagnosed with another type of cancer within the past 5 years, except for certain fully treated skin cancers or non-invasive cancers (confirm with trial site).
  • People who are currently enrolled in another clinical trial, or who have received another experimental drug or medical device within 4 weeks before the start of this trial.
  • People who have previously received certain immunotherapy treatments that target specific immune system proteins (such as anti-PD-1, anti-PD-L1, anti-PD-L2, or similar drugs).
  • People who have previously received certain targeted cancer therapies (such as those targeting VEGF/VEGFR, RAF, MAPK, PDGFR, or FGFR).
  • People who have received certain traditional Chinese medicines or immune-boosting drugs as a whole-body treatment within 2 weeks before the first dose of the study treatment (confirm with trial site for specific exceptions).
  • People who have an active autoimmune disease that has required whole-body treatment within the past 2 years (some replacement hormone therapies are not considered to be in this category — confirm with trial site).
  • People who have received steroid tablets or injections (not including nasal sprays, inhalers, or creams) or other immune-suppressing treatments within 7 days before the first dose of the study treatment.
  • People who have had an organ transplant or bone marrow/stem cell transplant from another person (corneal transplants are not included in this restriction).
  • People who have a known allergy to the study drug (sintilimab) or any of its ingredients.
  • People who have not yet recovered from side effects or complications of previous treatments (recovery is generally defined as returning to mild or baseline levels, not counting tiredness or hair loss).
  • People with a known history of HIV infection.
  • People with untreated, active hepatitis B infection (defined by specific blood test results — confirm with trial site).
  • People with active hepatitis C infection.
  • People who have received a live vaccine within 30 days before the first dose of the study treatment.
  • Women who are pregnant or breastfeeding.
  • People with other serious uncontrolled health conditions, as determined by the trial investigators.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026

Contact this trial

Principal Investigator: Guofang Zhao, MD, Ningbo No.2 Hospital

Phone: +86-574-83870605

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Ningbo No.2 Hospital
Registry
ClinicalTrials.gov
Start date
1 February 2024
Est. completion
28 February 2025

This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.

Primary endpoints

major pathological response (MPR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov