Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 18 and 65 years old
- You have been diagnosed with an anxiety disorder (such as Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, or a specific phobia), PTSD, OCD, or an adjustment disorder involving anxiety
- You are currently looking for or receiving mental health treatment
- You are able to read and understand a consent form and agree to take part
- English is your first language or the main language you speak fluently
Who may not be able to join:
- You have a moderate or severe alcohol or drug use problem (as defined by standard medical guidelines)
- You have ever been diagnosed with a psychotic disorder or bipolar disorder with mania
- You have a seizure disorder that would make brain stimulation or brain recording unsafe
- You have ever had a traumatic brain injury that caused you to lose consciousness
- You have a brain-related condition that gets worse over time, such as Alzheimer's disease, Parkinson's disease, or a similar condition
- You have a health condition that would make it very uncomfortable to sit or lie still for long periods of time
- You have any health reasons that would prevent you from having an MRI scan
- You have metal anywhere in your body
- You are currently pregnant
- You experience severe anxiety in enclosed spaces (claustrophobia)
- You are particularly sensitive to loud noises
- You have a medical condition or take treatments that increase your risk of having a seizure
- You have a history of severe brain injury
- You have a history of seizures or epilepsy
- You are currently taking certain medications, including anticholinergic drugs, antipsychotic medications, or sleeping/sedative medications (confirm with trial site if you are unsure whether your medication falls into these categories)
- You are currently taking opiate-based medications or substances on a regular basis
- You are currently taking naltrexone
- Note: certain medications such as SSRIs, cholinesterase inhibitors, or NMDA receptor antagonists may be allowed if you have been on a stable dose for at least four weeks before joining the trial (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Christopher Sege, PhD, Medical University of South Carolina
Phone: (843) 501-1718
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Fear-Potentiated Startle Reflex
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.