Gastro-oesophageal Reflux Disease Trial, Recruiting NCT06280664 Sponsor: University of Chicago Condition: Gastro-oesophageal Reflux Disease
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Gastro-oesophageal Reflux Disease Trial, Recruiting

NCT06280664
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 50 years of age
  • People who are able to understand and agree to participate in the study on their own
  • People with a Body Mass Index (a measure of body weight relative to height) below 30
  • People whose hiatal defect (a gap where the stomach can push up through the diaphragm) measures less than 4cm, as shown on a specific type of X-ray called an esophagram
  • People whose stomach acid levels are too high, specifically where acid levels drop below pH 4 for more than 5.5% of the time during pH testing (confirm with trial site)
  • People who are considered suitable for a specific type of surgery that closes the hiatal defect only

Who may not be able to join:

  • People under 18 years of age
  • People who are currently pregnant
  • People who are incarcerated (prisoners)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Yalini Vigneswaran, MD, University of Chicago

Phone: 773-702-6337

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
2 October 2020
Est. completion
1 October 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Concentration of pH testing

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov