Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older.
• People who are willing to sign a consent form approved by an Ethics Committee before any trial-related tests or procedures, and who are willing to follow the trial steps and attend required follow-up visits.
• People who have been diagnosed with pancreatic cancer that cannot be removed by surgery — either locally advanced (Stage 3) or with a small number of spread sites (Stage 4) — confirmed by a CT or MRI scan taken within 14 days before the planned procedure. If Stage 4, there must be no more than 5 tumors that have spread, those tumors must be in the liver and/or lungs only, and they must be stable.
• People who are not suitable for surgery and who have already received chemotherapy for at least 8 weeks.
• People who are able to safely receive general anesthesia.
• People who have a general health and activity level rated as 0 or 1 on a standard medical scale (meaning fully active or able to carry out light work), as assessed at the start of the trial.
• People whose blood test results, taken within 14 days before the planned procedure, meet specific minimum standards for blood cell counts, liver function, kidney function, and blood clotting (confirm with trial site for exact values).
• People whose main pancreatic tumor measures at least 2 cm at its widest point.
• People whose tumor is located at least 1 cm away from nearby digestive organs such as the small intestine, stomach, or colon, as seen on medical imaging.
• People whose tumor can be clearly seen using the ultrasound equipment used in this trial.
• People who will have only one pancreatic tumor treated during the procedure, even if more tumors are present in the pancreas.

Who may not be able to join:

• People who are pregnant, planning to become pregnant, or currently breastfeeding during the trial period.
• People who have previously had surgery on the pancreas, the bile system connecting to the intestine, or the stomach.
• People who are currently taking part in another clinical trial of a drug or medical device that has not yet completed its main study goals, or that could affect this trial's results.
• People who have a blood clotting problem that cannot be corrected.
• People whose life expectancy is less than six months.
• People who have a stent or drainage tube in the bile duct or pancreas that overlaps with the area planned for treatment.
• People whose cancer has spread to organs other than the liver or lungs (for example, to the bones, brain, or the lining of the abdomen).
• People who have a known allergy to contrast dye used in medical imaging and for whom pre-treatment medication cannot adequately manage that reaction.
• People who have an active ulcer in the stomach or the first part of the small intestine (duodenum) that requires medical treatment.
• People who have received chemotherapy within 7 days before the planned procedure date, noting that overall time off chemotherapy must not exceed 21 days in total.
• People who have received immunotherapy or targeted cancer therapies within 30 days before the planned procedure.
• People whose specific tumor being targeted has already been treated with a local therapy such as ablation, embolization, or radiation.
• People who have a cancer treatment other than chemotherapy (such as pancreatic surgery, targeted therapy, or immunotherapy) planned within 30 days after the procedure.
• People who have chemotherapy planned within 14 days after the procedure, noting that overall time off chemotherapy must not exceed 21 days in total.
• People who have not sufficiently recovered from side effects of chemotherapy or immunotherapy (confirm with trial site for specific recovery standards), not including hair loss, nerve-related side effects, or digestive enzyme problems.
• People for whom the treating investigator considers this procedure not to be an appropriate treatment option.
• People who have another health condition that could put their safety at risk or affect their ability to follow the trial requirements.
• People whose tumor cannot be reached or treated within the operating range of the trial's medical device.

Important: Always verify eligibility with the trial site directly before applying.