Phase 2 Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are between 45 and 75 years old at the time of signing the consent form
- People who have been diagnosed with Parkinson's disease within the past 4 to 10 years
- People whose Parkinson's diagnosis includes slowness of movement, plus at least one of the following: muscle stiffness, tremor at rest, or balance problems
- People who experience "motor fluctuations," meaning their movement symptoms change or wear off between doses of medication, as recorded in a Parkinson's movement diary
- People who have been on a stable Parkinson's medication routine for at least 4 weeks before the screening visit
- People whose symptoms respond to levodopa, a common Parkinson's medication
Who may not be able to join:
- People who have, or have had, other medical, genetic, or neurological conditions that could explain their symptoms instead of Parkinson's disease
- People with a significant history of blood vessel or heart disease
- People with notable memory or thinking difficulties, or poorly managed depression or anxiety
- People who have had, or currently have, psychosis or problems with impulse control
- People with a history of cancer, except for certain treated skin cancers (squamous or basal cell carcinoma)
- People with other health conditions that could make surgery unsafe or unsuitable (confirm with trial site)
- People who are unable to have an MRI scan or cannot receive a certain type of contrast dye used in MRI imaging
- People who have previously had brain surgery, including procedures such as deep brain stimulation, pallidotomy, focused ultrasound treatment, or other experimental brain procedures
- People who are currently on long-term medication that suppresses the immune system
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 919-388-1040
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from baseline to Month 18 on PD Motor Diary
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.