Phase 2 Myeloma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with a specific type of amyloidosis called AL amyloidosis, confirmed according to the trial's guidelines
• People whose disease can be measured through a specific blood test that looks at proteins called free light chains
• People who have already received at least one previous treatment for their condition and whose doctor believes they need further treatment
• People whose level of a heart-related protein in the blood (NT-proBNP) is at or below a certain level during the screening period
• People whose liver, blood, kidneys, and heart are all functioning adequately, as defined by the trial's guidelines
• People who are reasonably able to carry out daily activities, based on a standard medical scoring system (a score of 2 or lower on the ECOG scale)

Who may not be able to join:

• People who have a history of a different type of amyloidosis (other than AL amyloidosis)
• People whose bone marrow biopsy or sample shows more than 60% of a certain type of abnormal cell (plasma cells) during screening
• People found to have certain bone damage or tumours outside the bone marrow on imaging scans during screening
• People who have had a heart attack within the six months before their first screening visit
• People who have had an active infection requiring hospital care or treatment with intravenous (IV) antibiotics or antifungals within 28 days before starting the study drug

Important: Always verify eligibility with the trial site directly before applying.