Phase 2 Colorectal Cancer Trial, Recruiting NCT06307548 Sponsor: Roswell Park Cancer Institute Condition: Colorectal Cancer
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Phase 2 Colorectal Cancer Trial, Recruiting

NCT06307548
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older
  • You have colorectal cancer that has spread locally or come back, and you are scheduled to have surgery
  • You are able to have CT and MRI scans
  • You are well enough to carry out some daily activities (your doctor will assess your general health using a standard scale, and you need to score 3 or below out of 4)
  • If you could become pregnant, you must agree to use reliable birth control methods (such as hormonal contraception, barrier methods, or abstinence) before joining, and must inform your doctor immediately if you become or suspect you are pregnant during the study
  • You must understand the research nature of this study and sign a written consent form before any study procedures take place

Who may not be able to join:

  • Women who are pregnant or currently breastfeeding
  • Anyone who the study doctor feels is not a suitable candidate for the special light-guided surgery and light-based treatment used in this trial (confirm with trial site)
  • People who have a condition called porphyria, or who have had an allergic reaction to porphyrins or similar substances (confirm with trial site)
  • People who have not been medically cleared to have surgery
  • People who have active liver inflammation (hepatitis) or ongoing liver problems, shown by abnormal liver test results above a certain level
  • People with serious uncontrolled health conditions, such as an active infection, heart failure, unstable chest pain, an irregular heartbeat, or mental health or personal circumstances that would make it hard to follow the study requirements
  • People who are unwilling or unable to follow the study's requirements
  • Anyone who the study doctor considers unsuitable to receive the study treatment or procedures for any other reason (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Roswell Park Cancer Institute
Registry
ClinicalTrials.gov
Start date
30 July 2024
Est. completion
1 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Accuracy of the fluorescence imaging (Phase I); Incidence of adverse events (Phase I); Evidence of disease (Phase II); Changes in carcinoembryonic antigen (CEA) and circulating tumor deoxyribonucleic acid (ctDNA) (Phase II)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov