Phase 2 Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with wild-type transthyretin amyloid cardiomyopathy (a heart condition caused by protein build-up), confirmed through genetic testing, a bone scan, and/or a heart tissue biopsy.
- People who are currently taking water pills (loop diuretics) to manage fluid build-up.
- People whose heart failure symptoms fall into a moderate-to-severe range, as classified by a standard medical scale (New York Heart Association class II–IV).
- People aged 65 years or older.
- People whose heart is not pumping blood as efficiently as normal, based on measurements taken during a heart ultrasound (confirm with trial site for specific thresholds).
- People who have given their full agreement to take part, both verbally and in writing.
Who may not be able to join:
- People with moderate to severe narrowing of the aortic valve (mild valve changes alone would not necessarily prevent participation).
- People with other significant heart valve problems.
- People with serious blockages in the heart's arteries, such as blockage of the main left artery, blockage in three major arteries, or a heart attack within the past four weeks.
- People who cannot safely receive the medication dobutamine — for example, due to a known allergy to dobutamine or sulfites, a type of adrenal gland tumour (phaeochromocytoma), or a serious irregular heart rhythm called ventricular tachycardia.
- People with very advanced kidney disease, where the kidneys are functioning at a very low level.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 0045 91 65 18 48
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Cardiac output (CO)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.