Parkinson's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with Parkinson's Disease according to a specific standard diagnostic guideline (the UK Parkinson's Disease Society Brain Bank criteria)
• People aged between 30 and 80 years
• People whose Parkinson's disease is at a moderate stage (Stage II or III on the Hoehn and Yahr scale), measured while their medication is working
• People without severe thinking or memory difficulties, based on scores from two standard cognitive tests (MMSE score of 24 or above, and MoCA score of 17 or above out of 30)
• People who have been on a stable Parkinson's medication dose for a consistent period
• People whose physical condition allows them to complete a 6-Minute Walking Test
• People who are willing to take part, understand what the study involves, and are able to sign a consent form

Who may not be able to join:

• People who have a neurological condition other than Parkinson's disease
• People with bone or joint conditions that would affect their ability to walk or exercise
• People with a known heart or cardiovascular condition that could make the required physical activity unsafe
• People with diabetes or other metabolic or hormonal conditions
• People with uncontrolled high blood pressure (resting blood pressure above 150/90 mmHg)
• People with a condition where blood pressure drops significantly upon standing (orthostatic hypotension), or whose systolic blood pressure when standing falls below 100
• People with thyroid problems (overactive or underactive), abnormal liver function, or reduced kidney function based on blood test results
• People whose general blood test results fall outside the normal range in a way considered clinically significant by the medical team
• People who have recently used medications such as anti-anxiety drugs, sleeping pills, benzodiazepines, or antidepressants, unless the dose has been stable for at least 28 days before the screening visit
• People who have had a serious illness requiring hospital treatment or systemic medication in the last 4 weeks
• People with any other significant medical condition, mental health condition, drug or alcohol use, or abnormal test result that the investigators believe would interfere with participation
• People with a score above 28 on the Beck Depression Inventory II, which indicates severe depression that may prevent safe participation in exercise
• Women who are pregnant
• People with other conditions, injuries, or disorders that may affect their ability to exercise — such as a history of stroke, breathing problems, traumatic brain injury, orthopaedic injury, or neuromuscular disease

Important: Always verify eligibility with the trial site directly before applying.