Phase 3 Atrial Fibrillation Trial, Recruiting NCT06376916 Sponsor: Wake Forest University Health Sciences Condition: Atrial Fibrillation
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Phase 3 Atrial Fibrillation Trial, Recruiting

NCT06376916
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 years or older
  • People who are able to give informed consent (agree to participate after being told what the study involves)
  • People whose main diagnosis is a fast, irregular heartbeat called atrial fibrillation or atrial flutter, with a heart rate of 120 beats per minute or higher
  • People being treated with a medication called diltiazem to help slow their heart rate
  • People who speak English

Who may not be able to join:

  • People whose blood pressure is dangerously low (confirm with trial site for specific numbers)
  • People who are not fully conscious or aware
  • People with severe kidney failure who require dialysis (either hemodialysis or peritoneal dialysis)
  • People experiencing a sudden worsening of heart failure, as determined by a doctor's assessment and/or imaging
  • People whose fast heart rate is thought by medical staff to be the body's response to a different underlying condition
  • People with heart rhythm problems other than atrial fibrillation or atrial flutter, such as sick sinus syndrome or certain abnormal electrical patterns in the heart
  • People having a heart attack at the time of the trial
  • People who are pregnant, based on a positive pregnancy test
  • People who have a medical reason they cannot receive magnesium sulfate, including a condition called myasthenia gravis
  • People who have a known allergy or sensitivity to any of the medications used in the study
  • People who have already taken part in this trial at a previous visit
  • People who have previously withdrawn from this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Travis Hase, MD, Wake Forest University Health Sciences

Phone: (708) 684-1078

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
7 October 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ventricular rate control

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov