Myeloma Trial, Recruiting NCT06383143 Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia Condition: Myeloma
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Myeloma Trial, Recruiting

NCT06383143
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Part A

  • People who have been diagnosed with MGUS (a condition where abnormal proteins are found in the blood) with an abnormal result on a specific blood test called the free light chain ratio, or who have smouldering multiple myeloma (an early, symptom-free form of multiple myeloma)
  • People who have not yet received any treatment for their condition
  • People aged 18 years or older
  • People who are able to understand and are willing to sign a consent form
  • People who are planning to have their follow-up care at one of the participating medical centres

Part B

  • People who have been diagnosed with a condition called systemic AL amyloidosis (a disease where abnormal proteins build up and damage organs)
  • People who have not yet received any treatment for their condition
  • People aged 18 years or older
  • People who are able to understand and are willing to sign a consent form
  • People who are planning to have their follow-up care at one of the participating medical centres

Who may not be able to join:

Part A

  • People who have been diagnosed with a form of monoclonal gammopathy that is already causing symptoms
  • People who have previously received treatment for any monoclonal gammopathy condition

Part B

  • People whose amyloidosis is not the AL type
  • People who have previously received treatment for AL amyloidosis

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Registry
ClinicalTrials.gov
Start date
1 May 2023
Est. completion
1 May 2026

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Assess proportion of patients with newly diagnosed AL identified through the biomarker-based screening of at-risk patient; Assess the proportion of patients with deep haematological response after frontline therapy (best response evaluation) in the new enhanced, contemporary, real-world series of AL patients enrolled during the study.; 3. Identify associations of clonal light chain features with different clinical features at baseline.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov