Parkinson's Disease Trial, Recruiting NCT06388863 Sponsor: Shanghai Zhongshan Hospital Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT06388863
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Parkinson's disease (PD) according to Chinese diagnostic criteria, and are between 40 and 75 years old
  • Your Parkinson's disease is rated at a mild to moderate stage (Hoehn-Yahr stage 1–3) (confirm with trial site)
  • You have had at least 2 of the following bowel problems for at least 6 months, occurring regularly in the past 3 months: straining during more than 1 in 4 toilet visits; hard or lumpy stools more than 1 in 4 times; feeling like your bowels didn't fully empty more than 1 in 4 times; feeling like something is blocking your back passage more than 1 in 4 times; needing to use your hand to help pass stools more than 1 in 4 times; or having fewer than 3 natural bowel movements per week
  • You have been taking a stable, unchanged dose of your Parkinson's, antidepressant, or antipsychotic medications for at least 1 month
  • You do not have any warning signs such as unexplained weight loss or blood in your stools, and other possible causes of your symptoms have been ruled out
  • You are willing to take part and have signed a consent form

Who may not be able to join:

  • You have a condition similar to Parkinson's disease but with additional features (known as Parkinsonism-plus syndrome)
  • You have a history of stroke, brain injury, or epilepsy
  • You have previously had surgery specifically to treat your Parkinson's disease
  • You are pregnant, planning to become pregnant, or currently breastfeeding
  • You have a psychiatric condition or would have difficulty cooperating with treatment and follow-up appointments
  • You have a weakened immune system or are taking medication that affects your immune system
  • You have had abdominal (stomach area) surgery in the past, unless it was an appendix removal, gallbladder removal, caesarean section, or hysterectomy
  • You have diabetes, high blood pressure, thyroid disease, or another long-term condition that is not well controlled
  • You have used probiotics or antibiotics within the month before joining the study
  • You have serious heart, brain, kidney, or lung disease, or any form of cancer

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Shengdi Wu, Fudan University

Phone: (86)13817923359

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
21 February 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Response rate of constipation in Parkinson's Disease (PD)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov