Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 70 years old
- People who have been diagnosed with Major Depressive Disorder (a serious form of depression), either a single episode or recurring episodes, confirmed using a standard diagnostic interview
- People whose current depression scores at least 18 on a standard depression severity scale called the Hamilton Rating Scale for Depression (a measure used by doctors to assess how severe depression is)
- People whose depression has not meaningfully improved after trying two or more standard antidepressant treatments during their current episode
- People who have been on a stable psychiatric medication plan for at least 4 weeks before the initial screening appointment
- People whose thyroid, blood count, electrolyte, and liver test results are all within normal ranges based on pre-study blood tests
Who may not be able to join:
- People who have had a problem with substance abuse or dependence in the past 3 months
- People who have a serious unstable physical health condition, a cardiac pacemaker, or an implanted medication pump
- People who are currently showing active thoughts of suicide (as measured by a specific score on a clinical rating scale — confirm with trial site)
- People who are pregnant
- People who have ever been diagnosed with bipolar disorder (type I or II), schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder, or who are currently experiencing psychotic symptoms
- People who have a metal implant in their body or any other condition that would normally prevent someone from having an MRI or TMS procedure (confirm with trial site)
- People who take anti-seizure medications or sedative medications (benzodiazepines) at a dose above a certain daily threshold
- People whose psychiatric medication was newly started or had its dose changed within the 4 weeks before the screening appointment
- People who have previously undergone TMS (Transcranial Magnetic Stimulation, a type of brain stimulation therapy) at any point in the past
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Georg Kranz, PhD, The Hong Kong Polytechnic University
Phone: 27664838
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Montgomery-Asberg depression rating scale (MADRS)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.