Atrial Fibrillation Trial, Recruiting NCT06402617 Sponsor: Imperial College London Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT06402617
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with persistent atrial fibrillation (an ongoing irregular heartbeat) and your doctor has recommended a procedure called catheter ablation to treat it.
  • Your doctor has assessed you as a suitable candidate for catheter ablation.
  • You are willing and able to sign a consent form agreeing to take part in the trial.

Who may not be able to join:

  • You have previously had a catheter ablation procedure for atrial fibrillation or any other heart rhythm problem.
  • There is a medical reason why catheter ablation or general anaesthetic would not be safe for you, including a past allergic reaction to contrast dye used in scans, a blood clot inside your heart, or not having taken blood-thinning medication as required in the six weeks before the procedure.
  • You have moderate or severe heart valve disease, or you have an artificial heart valve.
  • You have moderate-to-severe heart failure, meaning your heart is pumping significantly less blood than it should, or you have significant heart failure symptoms affecting daily life.
  • You have any form of disease affecting the heart muscle (confirm with trial site).
  • You currently have an active infection or a fever.
  • You have severe disease affecting the blood vessels in your brain.
  • You are currently experiencing active bleeding in your digestive system.
  • You have a condition affecting your blood's ability to clot, you are considered at high risk of bleeding, or you cannot safely receive a blood-thinning medication called heparin.
  • Your kidney function blood test result is above a certain level, suggesting significantly reduced kidney function (confirm with trial site).
  • You are currently on, or likely to need, kidney dialysis or a similar kidney support treatment.
  • Your diabetes is not well controlled, based on recent blood sugar test results (confirm with trial site).
  • You have a cancer that currently requires treatment.
  • Your life expectancy is shorter than the length of the trial.
  • You are pregnant, or you could become pregnant and are not using a reliable form of contraception.
  • You are not able to give informed consent to take part in the trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Prapa Kanagaratnam, FRCP PhD, Imperial College London

Phone: ‭020 3312 6666‬

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
30 April 2024
Est. completion
1 October 2025

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Atrial fibrillation cycle length in coronary sinus and left atrial appendage

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov