Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Fracture Group:
- People between 18 and 85 years old
- People who have a single ankle fracture (of a specific type, known as AO/OTA types A–C) that is being treated with surgery
- People whose other injuries (outside of the broken ankle) are considered minor in severity
- People who can speak, read, and understand English
Control Group (no fracture):
- People between 18 and 85 years old
- People who can speak, read, and understand English
Who may not be able to join:
Fracture Group:
- People who were already being treated for a long-term (chronic) pain condition before the ankle injury
- People who are on a formal pain management agreement (sometimes called a "pain contract")
- People whose fracture was caused by an underlying disease (such as cancer), rather than an injury
- People who were taking gabapentin (a nerve pain medication) or opioid pain medications every day before joining the trial
Control Group:
- People who have ongoing long-term (chronic) pain or a current short-term (acute) pain condition
- People who have ever had a bone fracture
- People who are currently taking any pain medications
- People who have had any previous orthopaedic (bone or joint) surgery
- People who have had any surgery within the last 5 years
- People who have nerve damage in their hands or feet (peripheral neuropathy)
- People who have had a major surgery, or have a serious medical condition such as heart disease, metabolic disorders, kidney disease, neurological disorders, or severe psychiatric conditions — as determined by the lead researcher
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Roman Natoli, MD, PhD, Indiana University
Phone: 317-274-5264
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Chronic Pain Grading Scale; Douleur Neuropathique (Neuropathic Pain) 4; Assessment of Chronic Regional Pain Syndrome (CRPS); Central Sensitization measure; Pain Inhibitory Test
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.