Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) through a tissue or cell sample, where the tumour is considered removable by surgery or is on the borderline of being removable — this is assessed using detailed scan results and agreed upon by a team of specialists
• People whose cancer has not spread to distant parts of the body outside the pancreas
• Adults aged 18 or older
• People who are able to give their informed consent to participate
• People who are able to attend scheduled visits and follow the study requirements
• People who are generally well enough to carry out daily activities with little or no limitation (as measured by a standard scale used in cancer care)
• People whose blood cell counts meet minimum levels: enough white blood cells (neutrophils), platelets, and red blood cells (haemoglobin), as confirmed by blood tests
• People whose liver function, kidney function, and protein (albumin) levels fall within acceptable ranges, as confirmed by blood tests
• Men, or women who are not pregnant and not breastfeeding
• Women who could become pregnant must agree to use effective contraception starting 28 days before treatment begins and throughout the treatment period
• Men must agree to use a condom during sexual contact with someone who could become pregnant, both during treatment and for 6 months after treatment ends

Who may not be able to join:

• People who have moderate or severe nerve damage (peripheral neuropathy), meaning symptoms that interfere with everyday tasks such as using a phone, cooking, or handling objects
• People with serious or uncontrolled health conditions that could affect safe participation, such as unstable chest pain (angina), a heart attack within the past 6 months, an uncontrolled irregular heartbeat, severe heart failure, uncontrolled diabetes, a serious active infection (particularly if a blocked bile duct has not been adequately treated), or significant mental health or social difficulties
• People who are pregnant or breastfeeding
• People with known disease affecting the brain or central nervous system, with some exceptions for those whose brain involvement has already been successfully treated and is stable (confirm with trial site)
• People who have had another cancer within the past 5 years or currently have another untreated cancer — though non-melanoma skin cancers and early-stage cancers confined to where they started may be exceptions (confirm with trial site)
• People with a known allergy or sensitivity to any of the medicines used in this trial
• People who are currently misusing alcohol or illicit drugs
• People who are unable or unwilling to sign the consent form

Important: Always verify eligibility with the trial site directly before applying.